氯法齐明的作用功效是什么？副作用多不多

Clofazimine is a drug used to treat leprosy and can produce a complete sensitizing effect in the clinical treatment of multidrug-resistant tuberculosis. As the drug of choice for the treatment of neoplastic leprosy, this drug should usually be used in combination with dapsone. Clofazimine is used in combination with rifampicin or ethionamide to treat infections caused by strains that are resistant to sulfone drugs. What is the function of that? Are there many side effects?

The effects of clofazimine

Clofazimine exerts its antibacterial effect by interfering with the nucleic acid metabolism of MTB, binding to its DNA, inhibiting DNA-dependent RNA polymerase, and preventing RNA synthesis, thereby inhibiting bacterial protein synthesis.

Clinical studies have confirmed that clofazimine is more effective against multi-drug-resistant Mycobacterium tuberculosis. It is recommended to use it in combination with second-line anti-tuberculosis drugs for the treatment of MDR-PTB patients, which can significantly improve the treatment effect. This drug can significantly improve the patient's quality of life and have a positive effect on the patient's condition.

Clofazimine side effects

The side effects of clofazimine include: skin redness and pigmentation, dry skin and ichthyosis-like changes, nausea, vomiting, anorexia, abdominal pain, constipation, diarrhea, drowsiness, dizziness, insomnia, etc. The side effects of clofazimine are generally mild and do not affect treatment. Taking the drug with food can alleviate symptoms. If patients have serious adverse reactions during treatment, they should immediately go to the hospital for medical treatment, and the doctor will adjust the medication plan. Patients are not allowed to use other drugs without authorization.

The above is an introduction to the functions and side effects of Clofazimine. If patients want to know more about the drug information (such as drug prices, purchase channels, etc.), they can consult the medical companion travel service.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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