氯法齐明治疗瘤型麻风有作用吗？

Clofazimine was launched as a leprosy treatment drug in 1969 by the Swiss company Ciba Geigy, and was approved by the US FDA in 1986. At this stage, clofazimine is mainly used as the drug of choice for the treatment of tumorous leprosy, especially for the treatment of infections caused by strains resistant to sulfone drugs. Is there any effect in treating tumor leprosy?

The therapeutic effect of clofazimine

Clofazimine is the drug of choice for the treatment of neoplastic leprosy. Clofazimine has positive effects on leprosy, and is also very effective on patients with tumors that are resistant to sulfone drugs. It is manifested in the reduction of skin lesions and the significant decrease in bacterial morphological index. Clofazimine has both preventive and therapeutic effects on leprosy erythema nodosum. The incidence and severity of leprosy erythema nodosum in tumor-type patients treated with clofazimine are significantly lower than those in patients treated with DDS. For long-term glucocorticoid-dependent erythema nodosum, glucocorticoids can be gradually withdrawn after treatment with clofazimine.

Clofazimine Precautions

When patients receive clofazimine (Clofazimine) treatment, they should strictly follow the doctor's instructions, so as to maximize the efficacy of the drug and reduce the occurrence of side effects.

People with a history of gastrointestinal diseases or liver function impairment and those who are intolerant to clofazimine should use this drug with caution. Clofazimine should be taken with food or milk.

To prevent the development of resistance to clofazimine, patients should be treated with one or more other antileprosy drugs. In case of overdose of clofazimine, induce vomiting, gastric lavage, and catharsis, and provide symptomatic and supportive treatment if necessary.

The above is the introduction about clofazimine. If patients have other questions about clofazimine, they can consult the medical companion service.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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