埃索美拉唑和奥美拉唑的区别

The difference between esomeprazole and omeprazole:

Esomeprazole is a second-generation proton pump inhibitor, and omeprazole is a first-generation proton pump inhibitor.

Omeprazole is mainly used for duodenal ulcers and Zollinger-Ellison syndrome (gastrinoma), but can also be used for gastric ulcers and reflux esophagitis. Esomeprazole is used for the treatment of gastroesophageal reflux disease and erosive reflux esophagitis, and is a long-term maintenance treatment for cured esophagitis patients to prevent recurrence. Used in combination with appropriate antimicrobial therapy to eradicate Helicobacter pylori and heal duodenal ulcers associated with Helicobacter pylori infection to prevent recurrence of peptic ulcers associated with Helicobacter pylori infection.

The acid-suppressing effect of esomeprazole is stronger than that of omeprazole. The range of indications for omeprazole is wider than that of esomeprazole, and the side effects of esomeprazole are smaller than those of omeprazole.

The difference between esomeprazole and omeprazole usage and dosage:

Omeprazole enteric-coated tablets: (1) Peptic ulcer: 20 mg (1 tablet) once, 1 to 2 times a day. Swallow it every morning or once in the morning and evening.

(2) Reflux esophagitis: 20 to 60 mg (1 to 3 tablets) once, 1 to 2 times a day. Swallow it in the morning or once in the morning and evening.

(3) Zollinger-Ellison syndrome: 60 mg (3 tablets) once a day. The total daily dose can be adjusted to 20 to 120 mg (1 to 6 tablets) according to the condition. If the total daily dose exceeds 80 mg (4 tablets), it should be divided into two doses.

Esomeprazole magnesium enteric-coated tablets: (1) Treatment of erosive reflux esophagitis: 40 mg, once a day, for four weeks.

(2) Symptom control of gastroesophageal reflux disease: patients without esophagitis take 20 mg once a day.

(3) Combined with appropriate antibacterial therapy to eradicate Helicobacter pylori: and heal duodenal ulcers related to Helicobacter pylori, and prevent the recurrence of peptic ulcers related to Helicobacter pylori: Esomeprazole magnesium enteric-coated tablets 20 mg + amoxicillin 1g + clarithromycin 500 mg, twice a day for 7 days.