埃索美拉唑肠溶胶囊效果怎么样

Esomeprazole is used for the treatment of gastroesophageal reflux disease (GERD) and erosive reflux esophagitis. Long-term maintenance treatment to prevent recurrence in patients with cured esophagitis. Symptom control of gastroesophageal reflux disease (GERD). When used in combination with appropriate antibacterial therapy to eradicate Helicobacter pylori, heal duodenal ulcers related to Helicobacter pylori infection, and prevent the recurrence of peptic ulcers related to Helicobacter pylori, how effective is esomeprazole enteric-coated capsules?

To analyze the HP eradication rate and efficacy of esomeprazole enteric-coated capsules in patients with duodenal ulcer.

Methods: 100 patients with duodenal ulcers were randomly divided into a control group and an experimental group, 50 cases in each group. The patients in the control group were given omeprazole, and the experimental group was given esomeprazole enteric-coated capsules. The clinical treatment effects and HP eradication rates of the two groups were compared.

Results: After treatment, there was no statistically significant difference in the total effective rate, HP eradication rate, adverse reaction rate, and abdominal pain relief rate between the two groups of patients after 3 days of treatment (P>0.05). One day after treatment, the abdominal pain relief rate of patients in the experimental group was 42.0%, which was significantly higher than the 22.0% in the control group (P<0.05).

Conclusion: Esomeprazole enteric-coated capsules have the characteristics of significant clinical effect, high HP eradication rate and low incidence of adverse reactions in the treatment of duodenal ulcer, and are worthy of promotion and application.

Precautions when using esomeprazole:

1. Patients with rare hereditary diseases such as fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency should not take esomeprazole.

2. Renal impairment: Patients with renal impairment do not need to adjust the dose. For patients with severe renal insufficiency, caution should be used during treatment due to limited experience with this drug.

3. Hepatic impairment: Patients with mild to moderate hepatic impairment do not need to adjust the dose. In patients with severe hepatic impairment, the dose of esomeprazole should not exceed 2 mg.