埃索美拉唑和奥美拉唑哪个效果好

Esomeprazole and omeprazole are both proton pump inhibitors, which reduce gastric acid secretion and prevent the formation of gastric acid. Esomeprazole is the S isomer of omeprazole. Esomeprazole has the same effect as omeprazole. Which one is more effective, esomeprazole or omeprazole?

Objective To compare the clinical effects of esomeprazole and omeprazole in the treatment of gastric ulcer.

Methods: 200 gastric ulcer patients admitted from March 2017 to March 2019 were selected and randomly divided into an observation group and a control group, with 100 cases in each group. The observation group was treated with omeprazole, and the control group was treated with esomeprazole. Compare the clinical effects and adverse reactions of the 2 groups.

Results After treatment, the clinical symptom scores of both groups were higher than before treatment, and the observation group was higher than that of the control group (P 0. 01); the ulcer healing rate and Hp eradication rate of the observation group were higher than those of the control group, and the nocturnal acid breakthrough rate was lower than that of the control group (P 0. 05 or P 0. 01); there was no statistically significant difference in the incidence of adverse reactions between the 2 groups (P 0. 05).

Conclusion: Esomeprazole is more effective in treating gastric ulcers, effectively promotes ulcer healing, and is worthy of clinical promotion and application.

Esomeprazole and omeprazole are currently commonly used proton pump inhibitors, both of which have the effect of suppressing acid and protecting the stomach. Relatively speaking, esomeprazole is a more advanced proton pump inhibitor. It is of a higher level than omeprazole, so it is more effective than omeprazole.

Esomeprazole is a type of PPI drug and is the s isomer of omeprazole. It reduces gastric acid secretion through a specific targeting mechanism. Clinically, it is mainly used for the treatment of gastroesophageal reflux disease, peptic ulcer, eradication of Helicobacter pylori and other related gastric acid suppression treatments.

When taking esomeprazole, the tablets should be swallowed whole together with the liquid. They should not be chewed or crushed, otherwise the efficacy of the drug will be affected. For patients who cannot swallow, esomeprazole can be dissolved in carbonate-free water and administered through a gastric tube.