埃索美拉唑可以长期吃吗

Esomeprazole reduces gastric acid secretion through a specific targeting mechanism. It is concentrated in the high-acid environment of parietal cell acid secretion microtubules and converted into an active form, thereby inhibiting H+/K+-ATPase (proton pump), inhibiting both basic gastric acid secretion and stimulated gastric acid secretion. Can esomeprazole be taken long-term?

Any drug taken for a long time will have certain side effects, so esomeprazole magnesium enteric-coated tablets cannot be taken for a long time. Generally, it can be discontinued after 4-8 weeks.

Different conditions require different treatment courses for esomeprazole magnesium enteric-coated tablets. However, medicines have side effects and any medicine is not suitable for long-term use. Adverse reactions include side effects and toxic reactions. Side effects are inherent and unavoidable with drugs, but they are not harmful. The toxic effects are very harmful and can be avoided. Long-term use will have toxic effects, so it is recommended that you do not take certain drugs for a long time, including esomeprazole magnesium enteric-coated tablets.

In addition, adverse reactions of using esomeprazole include:

1. Central and peripheral nervous system: abnormal sensation, drowsiness, insomnia, and dizziness. Reversible confusion, agitation, aggression, depression and hallucinations, mainly in patients with severe disease.

2. Endocrine: Gynecomastia.

3. Gastrointestinal tract: stomatitis and gastrointestinal candidiasis.

4. Hematology: leukopenia, thrombocytopenia, agranulocytosis, pancytopenia.

5. Liver: encephalopathy (those with previous severe liver disease); jaundice or non-icteric hepatitis; liver failure.

6. Musculoskeletal: joint pain, muscle weakness and myalgia.

7. Skin: rash, photosensitivity, erythema multiforme, Stevens-Johnson syndrome, toxic epithelial necrosis, alopecia.

8. Others: discomfort. Allergic reactions, such as fever, bronchospasm, interstitial nephritis. Hyperhidrosis, peripheral edema, blurred vision, dysgeusia, and hyponatremia.

The above is about the long-term use of esomeprazole!