日本处方药埃索美拉唑怎么样

The Japanese prescription drug esomeprazole is a proton pump inhibitor and is used for the initial and long-term treatment of gastroesophageal reflux disease (GORD), including erosive reflux esophagitis (including erosive esophagitis). It can be used for the long-term maintenance treatment of esophagitis and the prevention of GORD recurrence, as well as the symptomatic treatment of GORD disease.

What about the Japanese prescription drug esomeprazole when combined with antibiotics to eradicate Helicobacter pylori, treat duodenal ulcers caused by Helicobacter pylori, and prevent the recurrence of peptic ulcers related to Helicobacter pylori? 

To observe the efficacy and safety of esomeprazole enteric-coated capsules in the treatment of duodenal ulcer. 

Methods 102 patients with duodenal ulcer admitted from December 2009 to February 2012 were selected as the research subjects. The patients were randomly divided into two groups. The experimental group (n=51) was treated with esomeprazole enteric-coated capsules, and the control group (n=51) was treated with esomeprazole tablets. The efficacy of the two groups of patients was observed and compared.

Results After treatment, the ulcer healing rate of patients in the experimental group was not significantly different from that of the control group, P>0.05; the symptom improvement rate of the experimental group was higher than that of the control group, and the clearance rate of Helicobacter pylori was higher than that of the control group, P<0.05. The difference was statistically significant; 5 patients in both the experimental group and the control group had adverse reactions, and the difference in the incidence of adverse reactions between the two groups was not significant and had no statistical significance (P>0.05). 

Conclusion: Esomeprazole enteric-coated capsules are effective in treating duodenal ulcer and are worthy of application in clinical work. 

In addition, medication during pregnancy and lactation: Although animal experiments show that esomeprazole has no fetal toxicity or teratogenic effects, it is generally not used in pregnant women and should be used with caution in lactating women. 

Use with caution in persons with known hypersensitivity to esomeprazole, other benzimidazoles, or any other component of this drug.

Medication for patients with poor liver and kidney function: For patients with severe liver function impairment, the daily dosage should not exceed 20mg.

Adverse reactions of esomeprazole include: occasional headache, diarrhea, constipation, abdominal pain, bloating, elevated serum aminotransferases, drowsiness, insomnia and dizziness, and rare rash.