枢丹副作用

(Ondansetron hydrochloride) is a potent and highly selective 5-HT3 receptor antagonist with strong antiemetic effects. Chemotherapy drugs and radiotherapy can cause the release of 5-HT in the small intestine, which activates the afferent branch of the vagus nerve through 5-HT3 receptors and triggers the vomiting reflex. This product blocks the triggering of this reflex. The stimulation of the afferent branch of the vagus nerve can also cause the release of 5-HT in the Postrema area at the bottom of the fourth ventricle, thereby strengthening it through the central mechanism.

Shudan (ondansetron hydrochloride) exerts an antiemetic effect on nausea and vomiting caused by chemotherapy and radiotherapy by antagonizing the 5-HT receptors of neurons located in the peripheral and central nervous systems. The mechanism of postoperative nausea and vomiting is unknown, but it may be induced by a common pathway similar to cytotoxic drugs that cause nausea and vomiting. Shudan (ondansetron hydrochloride) can still inhibit opioid-induced nausea, but its mechanism of action is unclear. Due to the highly selective effect of this product, it does not have the side effects of other antiemetics, such as extrapyramidal reactions, excessive sedation, etc.

While the drug exerts its efficacy, it will also bring some side effects. What are the side effects of Shudan (ondansetron hydrochloride)?

The instructions for Shudan (ondansetron hydrochloride) show that Shudan may cause headache, abdominal discomfort, constipation, dry mouth, rash, occasional bronchial asthma or allergic reactions, and transient asymptomatic increases in transaminases. Rare reports of movement disorders, epileptic seizures, chest pain, arrhythmia, hypotension, and bradycardia have been reported.

Each patient's constitution and disease stage are different, and the side effects of using Shudan (ondansetron hydrochloride) will also be different, which is determined according to the patient's constitution. (Ondansetron Hydrochloride) Side effects are mostly mild, and patients do not need to worry too much about side effects. If serious side effects occur, patients need to inform the attending doctor in time for treatment.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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