止吐药阿瑞匹坦的效果怎么样

Aprepitant, an NK1 receptor antagonist developed and marketed by Merck, is used in combination with other antiemetics to prevent nausea and vomiting caused by chemotherapy drugs. The recommended dose is to be taken orally 1 hour before chemotherapy. Patients can take the drug with or without food. It is a drug that is more convenient to take. Aprepitant is a dose-dependent CYP3A4 inhibitor. Today we will learn more about the effect of the antiemetic drug aprepitant.

94 patients with lung cancer were treated with aprepitant on the basis of the same cisplatin-containing regimen as the control group. The vomiting conditions of the two groups of patients during the chemotherapy cycle were compared. The effective rate of acute vomiting treatment was 83.3% in the study group and 77.5% in the control group. The effective rate in the treatment of delayed vomiting was 92.6% in the study group, which was significantly higher than 75.0% in the control group. It can be seen that the effect of aprepitant in treating vomiting is very obvious and can improve the quality of life of patients.

Of course, the time it takes for aprepitant to take effect is also related to the specific disease and drug. Some diseases take a few weeks to take effect, and some diseases may take longer. When taking the drug, patients should pay attention to the completeness and duration of treatment.

Aprepitant is a selective high-affinity antagonist of the human substance P neurokinin 1 (NK1) receptor. It is generally well tolerated, but it still has side effects. Common adverse reactions of aprepitant are drowsiness, constipation, headache, hiccups, anorexia, increased liver index alanine aminotransferase values, nausea, hair loss, and diarrhea. Patients should pay more attention to their own changes when using it. If they have any intolerable reactions, they must communicate with their doctor in time.

Aprepitant is currently on the market in China, and patients who purchase it in domestic hospital pharmacies can be reimbursed by medical insurance, which relieves patients a lot of financial burden. However, patients can also obtain the drug through overseas medical service agencies such as Medical Companion Travel, which is more cost-effective, and it is sent directly from the pharmaceutical factory, which not only ensures the authenticity of the drug, but also avoids the trouble of going through multiple procedures. Patients can consult the Medical Companion Travel service staff for specific drug prices.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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