枢丹多久起效？

Shudan (ondansetron hydrochloride) is an antiemetic drug. It is a potent and highly selective 5-HT3 receptor antagonist with strong antiemetic effect. Chemotherapy drugs and radiation therapy can cause the release of 5-HT in the small intestine, which activates the afferent branch of the vagus nerve through 5-HT3 receptors and triggers the gag reflex. Ondansetron Hydrochloride Tablets are used for nausea and vomiting caused by cytotoxic drug chemotherapy and radiation therapy; prevention and treatment of nausea and vomiting after surgery.

(1) Adults: ① For vomiting caused by highly emetic chemotherapy drugs: 8 mg of intravenous central tablets 15 minutes before chemotherapy, 4 hours, and 8 hours after chemotherapy, and 8 mg of ondansetron tablets (2 tablets) taken orally every 8-12 hours after stopping chemotherapy for 5 days. ② For vomiting caused by chemotherapy drugs that are not very emetic: take 8 mg of Shudan (2 tablets) intravenously 15 minutes before chemotherapy, and then take 8 mg of Shudan (2 tablets) orally every 8-12 hours for 5 days. ③ For vomiting caused by radiotherapy: the first dose of 8 mg tablets (2 tablets) must be taken orally 1-2 hours before radiotherapy, and 8 mg (2 tablets) taken every 8 hours thereafter. The course of treatment depends on the course of radiotherapy. ④ For the prevention of nausea and vomiting after surgery: Inject 4mg (1 tube) intravenously at the same time during anesthesia. ⑤ For high-dose cisplatin, 20 mg of dexamethasone sodium phosphate can be added intravenously before chemotherapy, which can enhance the efficacy of Shudan on vomiting caused by highly emetic chemotherapy.

(2) Children: Inject intravenously at a dose of 5 mg/m2 (body surface area) before chemotherapy, and then take it orally 12 hours later; after chemotherapy, oral administration should be continued for 5 days.

How long does it take for Shudan to take effect?

(Ondansetron Hydrochloride) The specific onset of effect varies from person to person. We hope that patients will use the medication correctly under the guidance of a doctor.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

Recommended related articles: