阿瑞匹坦在药店能买到吗？

Aprepitant is the world's first approved NK-1 receptor antagonist antiemetic drug. It is characterized by crossing the blood-brain barrier and occupying NK-1 receptors in the brain with high selectivity and high affinity, thereby inhibiting the root cause of CINV at the central level. It is a drug used to prevent acute and delayed nausea and vomiting during initial and repeated treatment with highly emetogenic anti-tumor chemotherapy. So can I buy it in pharmacies?

Aprepitant is available at pharmacies. Aprepitant has been approved for marketing in my country, and patients in China can purchase and use the drug with hospital prescriptions. On March 29, 2014, Merck China announced in Beijing that aprepitant, a drug it developed to prevent nausea and vomiting caused by chemotherapy, has been approved by the China Food and Drug Administration to be marketed in China under the trade name: Yimei. As the world's first highly selective NK-1 receptor antagonist, aprepitant capsules bring good news to the vast number of Chinese chemotherapy patients. According to relevant media data, the sales of terminal aprepitant capsules in public hospitals in key domestic provinces and cities in 2018 were US$74.78 million, a year-on-year growth rate of 14.31%. The overall domestic market has reached a scale of US$200 million, with Merck’s Italian-American monopoly on the market.

The therapeutic effect of aprepitant is good, and its safety is reassuring to patients. The overall safety of aprepitant was evaluated in approximately 6,500 patients. The Domestic Clinical Trial of Highly Emetogenic Chemotherapy (HEC) conducted a randomized controlled clinical study in Chinese patients receiving highly emetogenic anti-tumor chemotherapy (HEC). In this study, 412 patients received aprepitant in the first cycle of chemotherapy, and 240 patients continued into the second phase of chemotherapy. The dosing regimen of aprepitant plus granisetron and dexamethasone (treatment group) was generally well tolerated. The main clinical adverse events were mild to moderate.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.