达那唑(Danocrine)的副作用及注意事项概览

Introduction: It is an anti-gonadotropin drug, which is clinically used to treat endometriosis, fibrocystic breast disease, etc. However, during treatment, it may cause side effects such as weight gain, hair loss, acne, changes in menstrual cycle time, edema, etc., which can be dealt with by adjusting diet, paying attention to voice use, medication, and adjusting treatment plans.

Danocrine side effects

Skin, such as acne or allergic reactions such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. Stomach discomfort, such as loss of appetite, stomach pain, nausea. Respiratory symptoms may include a sore throat, a cough with bloody mucus, or vomit that looks like coffee grounds. Jaundice (yellowing of the skin or eyes) may occur in the hepatobiliary system.

Systemic reactions, such as swelling or weight gain, hoarseness or deepening of the voice, hair loss or increased hair growth, bloody or tarry stools, dark urine, unexplained muscle pain, tenderness, or weakness, flushing (sudden warmth, redness, or tingling sensation).

Other problems such as changes in your menstrual cycle, unusual vaginal bleeding or spotting, breast changes, mood changes, nervousness, vaginal dryness or irritation, etc.

In addition, patients may also experience some serious side effects, such as increased pressure within the skull, manifesting as severe headache, tinnitus, dizziness, nausea, vision problems, and pain behind the eyes. Signs of blood clots include sudden numbness or weakness, vision or speech problems, swelling or redness in the arms or legs.

Methods for dealing with side effects

For women with menstrual changes, they can understand whether these changes are normal treatment reactions under the evaluation of a doctor. If necessary, they can reduce the drug dosage or use other drugs according to the doctor's advice. For patients with gastrointestinal discomfort, they can eat small meals frequently and avoid foods that are too greasy, spicy or irritating. If necessary, use antacids or gastric mucosal protectants under the guidance of a doctor to relieve symptoms. Patients with throat discomfort should avoid excessive use of their throats, such as talking loudly, and drink plenty of fluids.

For patients with breast swelling and pain, it is recommended to choose a supportive and comfortable bra to reduce breast pressure. It can also be combined with local heat compress to help reduce pain. Patients who gain weight should follow a balanced diet, control caloric intake, and avoid high-sugar and high-fat foods. You can also increase your daily activities and perform aerobic exercise and strength training to help control your weight. When hot flashes occur, wear breathable clothing, use a fan or air conditioner to lower the ambient temperature, and take deep breaths or apply cold compresses.

Precautions

Pregnant patients should not use Danocrine to avoid harming the unborn baby or causing birth defects. They should pay attention to contraception during use. Breastfeeding women should also avoid using Danocrine to avoid harming the baby. Danocrine is not approved for use by people under 18 years of age.

If you miss a dose of Danocrine, take it as soon as possible, but if it is almost time for your next dose, skip the missed dose and do not take two doses at once to avoid overdose. Women taking Danocrine to treat endometriosis should start taking it during their menstrual period. Danocrine is usually taken for 3-9 months to treat endometriosis. At the same time, you should pay attention to observe your own adverse reactions during treatment, and consult a doctor in time to deal with any discomfort.