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Side effects of danazol

Side effects of danazol include weight gain, acne, and seborrhea. Mild hirsutism, edema, alopecia, and voice changes manifested as hoarseness, sore throat, or unstable or deepened voice may occur and may persist after discontinuation of treatment. Other possible endocrine effects are menstrual disturbances including spotting, cycle timing changes, and amenorrhea.

Management of side effects of danazol

1. Menstrual disorders: It may lead to menstrual disorders, such as increased menstrual flow, prolonged menstrual time, etc. If the symptoms are mild, no special treatment is usually required and symptoms will gradually subside after the medication is stopped. If the symptoms of menstrual disorder are severe, it is recommended to seek medical treatment in time. The doctor may adjust the dosage of the drug or change the drug according to the specific situation.

2. Allergic reaction: If the patient is allergic to danazol, he may experience symptoms such as skin itching, redness and swelling, and in severe cases, anaphylactic shock. In the event of an allergic reaction, the medication should be stopped immediately and medical attention should be sought. The doctor may give anti-allergic drugs, such as loratadine, cetirizine hydrochloride, etc. for treatment.

3. Gastrointestinal reactions: After taking danazol, patients may experience gastrointestinal discomforts such as nausea, vomiting, abdominal pain, and diarrhea. It is recommended to take omeprazole enteric-coated tablets, sucralfate chewable tablets and other drugs for treatment under the guidance of a doctor, and at the same time adjust your eating habits and avoid eating spicy and irritating foods.

4. Headache: Long-term use of danazol may cause endocrine disorders, thereby causing headaches. Patients can take ibuprofen sustained-release capsules, acetaminophen tablets and other drugs for treatment under the guidance of a doctor to relieve pain.

5. Liver function damage: Danazol may cause liver function damage, causing symptoms such as yellowing of the skin and loss of appetite. It is recommended that patients check their liver function regularly and take compound glycyrrhizin tablets, liver-protecting tablets and other drugs for treatment under the guidance of a doctor to protect the liver.

If the patient develops any symptoms of discomfort while taking danazol, he should seek medical advice promptly so that the doctor can adjust the drug dosage or change the drug according to the specific situation. At the same time, patients should avoid eating spicy food, maintain adequate sleep time, and avoid staying up late and overexertion while taking danazol.

For more information on the precautions for danazol, please click: This article has a detailed introduction.

Contraindicated groups for danazol

1. Patients allergic to danazol: If the patient is allergic to danazol or any of its components, use of this drug may cause severe allergic reactions, such as difficulty breathing, rash, itching, etc. Therefore, it should be contraindicated in patients allergic to danazol.

2. Patients with heart, liver, and renal dysfunction: Danazol may cause damage to the heart, liver, and kidneys, so patients with cardiac, liver, or renal insufficiency should not take it.

3. Patients with abnormal genital bleeding: Danazol may cause genital bleeding, so patients with abnormal genital bleeding should not take it.

4. Patients with androgen-dependent tumors: Danazol has androgen-like effects and may promote the growth of androgen-dependent tumors, so it should be contraindicated in patients with such tumors.

5. Pregnant and lactating women: Danazol may have adverse effects on the fetus and infant, so it should be contraindicated by pregnant and lactating women.

6. Patients with epilepsy, migraine, diabetes and other diseases should also use danazol with caution because the drug may aggravate the symptoms of these diseases. Athletes should also use danazol with caution as it may result in a positive doping test.

7. Patients with thrombosis: Danazol may increase the risk of thrombosis, so patients with thrombosis, such as venous thrombosis, arterial thrombosis, etc., should not use danazol.

Before using danazol, patients should explain their health conditions and allergic history to the doctor in detail, so that the doctor can judge whether the drug is suitable for use. At the same time, patients should strictly follow the doctor's instructions when using drugs and avoid increasing or decreasing the dosage or changing the medication method on their own.

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