How effective and safe is dienogest for the treatment of endometriosis?

Endometriosis refers to the occurrence, growth, infiltration, and repeated bleeding of endometrial tissue (glands and stroma) in the endometrium covering the uterine cavity and in parts other than the uterus, which in turn causes pain, infertility, and nodules or masses. There are still some patients who do not show significant improvement after surgery and require long-term medication, and the recurrence rate is extremely high. It is a new generation of oral high-efficiency progesterone and the only progesterone in the world that specifically treats endometriosis. Progesterone is currently internationally recognized as a first-line/class A drug for the treatment of endometriosis.

So, how effective is dienogest, which is used to treat endometriosis?

Study the effect of dienogest in the treatment of endometriosis. Methods 83 patients with endometriosis were divided into low-dose group (41 cases) and high-dose group (42 cases) using random number table method. The low-dose group was given low-dose dienogest, and the high-dose group was given high-dose dienogest. The therapeutic effects of the two groups of patients were observed. Results In the low-dose group, 10 cases were markedly effective, 21 cases were effective, and 10 cases were ineffective, with a total effective rate of 75.61%; in the high-dose group, 30 cases were markedly effective, 10 cases were effective, and 2 cases were ineffective, and the total effective rate was 95.24%. The difference in the total effective rate between the two groups was statistically significant (P0.05). Conclusion: Dienogest 10 mg/time is effective in treating endometriosis and is safe, so it is worthy of clinical promotion.

So, how safe is dienogest?

Dienogest has a significant therapeutic effect, but there are also side effects after taking the drug. Headache, breast discomfort, including breast swelling and pain, amenorrhea, irregular bleeding, headache, chest discomfort, depression and acne are common side effects of dienogest. Usually these side effects will disappear after stopping the drug or gradually disappear after a period of treatment. Patients do not need to worry too much. Pay attention to their own reactions during the treatment. If there is any intolerance, promptly communicate with the doctor for symptomatic treatment.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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