What are the advantages of dienogest treating endometriosis?

The cause of adenomyosis is unknown, but as we all know, endometriosis is a hormone-dependent disease, and adenomyosis is also a hormone-dependent disease. Therefore, the drugs used to treat adenomyosis are roughly the same as those used to treat endometriosis, and most of them are hormone drugs. Dienogest has long been on the market in Japan. 2 mg per day can significantly improve the pain symptoms of patients with endometriosis, and its efficacy is equivalent to GnRH-a. Domestic research has also verified its effectiveness and safety. The State Food and Drug Administration approved (Dienogest) for marketing in my country in December 2018. Dienogest can also be used to treat adenomyosis and can be maintained long-term. So do you know what are the advantages of dienogest in treating endometriosis?

The advantages of Dienogest are reflected in three aspects. The first aspect is that it can treat pain and shrink lesions. Pelvic pain and dyspareunia are the main complaints of patients with endometriosis and are also the main focus of drug treatment. Dienogest can significantly improve dysmenorrhea and chronic pelvic pain; the second aspect is that dienogest can improve patients' fertility. The drug still has a good effect on recurrent endometriosis and avoids the damage to fertility caused by repeated surgical treatments. The third aspect is that dienogest can inhibit recurrence. A study included 203 patients with chocolate cysts. Dienogest was given 2 mg/d after surgery and used continuously for 12 months. After an average follow-up of 30 months, only 3 patients relapsed, with a recurrence rate of only 1.5%, suggesting that dienogest can effectively prevent recurrence and avoid repeated surgical injuries.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.