恩瑞格应怎么使用呢？

In the process of use, if the patient starts using it without knowing its usage and dosage, it is very likely to cause adverse reactions. If you do not take medication as prescribed, it will do a lot of harm to your body without any benefit. So how should Enrig be used?

The recommended starting daily dose of Enrig is 20 mg/kg. For patients who receive monthly transfusions of more than 14 mL/kg of packed red blood cells (i.e., more than 4 units/month in adults) and who need to reduce excess iron exposure, a starting dose of 30 mg/kg/day may be considered. For patients who receive monthly transfusions of less than 7 mL/kg of packed red blood cells (i.e., less than 2 units/month in adults) and who need to maintain body iron balance, a starting dose of 10 mg/kg/day may be considered. In patients who have already responded well to deferoxamine therapy, an initial dose of Enriga equivalent to half the deferoxamine dose may be considered. (For example, a patient receiving deferoxamine 40 mg/kg/day, 5 days per week, or equivalent, may start with 20 mg/kg if switched to Enrig.) Preparation: Enrig should be taken on an empty stomach at least 30 minutes before a meal, once a day, preferably at the same time every day. Tablets should not be chewed or swallowed whole. 

Enrige should not be taken with aluminum-containing antacids, and the dosage (mg/kg) needs to be calculated and rounded to the nearest whole tablet. Completely dissolve the tablets in water, apple juice or orange juice (100-200 mL) by stirring until a clear suspension is obtained and drink it. The remaining drug must be added to a small amount of water, apple juice or orange juice and mixed well before taking. Dissolving in carbonated drinks and milk is not recommended as it can cause foaming and slow dispersion. It is used to treat chronic iron overload in patients with beta-thalassemia older than 6 years old due to frequent blood transfusions (monthly administration of concentrated red blood cells ≥7mL/kg); for children under 6 years old and iron overload caused by other transfusion-dependent diseases, it is recommended to use with caution based on the specific conditions of the patient.