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How long to eat? There is no unified answer to the question of how long you need to take Deferasirox (Enreg), because each patient's condition and physical condition are different, so the time to take Deferasirox (Enreg) is also different. It is recommended to consult the attending doctor before taking the medicine.
The starting dose of Enrige is 20mg/kg. For patients who receive monthly transfusions of more than 14 mL/kg of packed red blood cells (ie, more than 4 units/month in adults) and who need to reduce excess iron exposure, a starting dose of 30 mg/kg/day may be considered. For patients who receive monthly transfusions of less than 7 mL/kg of packed red blood cells (i.e., less than 2 units/month in adults) and who need to maintain body iron balance, a starting dose of 10 mg/kg/day may be considered. In patients who have already responded well to deferoxamine therapy, an initial dose of Enriga equivalent to half the deferoxamine dose may be considered.
Recommended for patients with iron accumulation, such as those who require long-term blood transfusion (blood transfusion volume up to 100 ml/kg) and serum ferritin exceeds 1000 μg/L; corresponding to the body weight, it is initially recommended to take a daily dose of 20 mg/kg of Deferasirox (Enrig). Depending on the improvement of serum ferritin indicators, patients may need to adjust or increase the dose of Deferasirox (Enrig). Generally, the dose will be increased in units of 5 mg/kg or 10 mg/kg, but the total dose should not exceed 30 mg/kg per day.
Deferasirox should be taken once daily on an empty stomach, at least 30 minutes before a meal, preferably at the same time each day. Tablets should not be chewed or swallowed whole. The tablets can be completely dissolved in water, apple juice or orange juice by stirring until a clear suspension is obtained and then consumed. The remaining drug must be added with a small amount of water, apple juice or orange juice and mixed well before consumption. Not recommended for dissolution in carbonated drinks or milk as it can cause foaming and slow dispersion.
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