非布司他好吗？

Gout is a serious disease that may be difficult to cure. It is a commonly used drug to treat gout and hyperuricemia. It is also the drug of choice for inhibiting purine production. So, is the treatment effect of febuxostat good?

Febuxostat and allopurinol have similar properties and are both drugs that inhibit uric acid production. After comparing the two drugs clinically, it was found that febuxostat has a better acid-lowering effect.

Febuxostat lowers uric acid faster. In actual medication, allopurinol starts with a small dose and is gradually increased until the uric acid reaches the target. This process is very slow. However, after taking 40mg or 80mg of febuxostat once, uric acid can reach the standard within 1-2 weeks.

Febuxostat is more suitable for patients with hyperuricemic gout. Generally speaking, there are three main types of high uric acid in gout patients: poor uric acid excretion type, excessive uric acid production type, and mixed type. Febuxostat is a 2-arylthiazole derivative and a xanthine oxidase inhibitor that reduces serum uric acid concentration by inhibiting uric acid synthesis, so it is more suitable for patients with excessive uric acid production.

It is recommended that gout patients should take a 24-hour urine test to check for uric acid before deciding to take febuxostat to determine the type of high uric acid.

In addition, with the progress of social economy and changes in dietary structure, the voice of "gout" will sound. Relevant reports in recent years: The number of patients with hyperuricemia in my country has reached 120 million, of which nearly 80 million are gout patients. Elevated uric acid in the blood can cause the familiar "gout", which causes redness, swelling, heat, and pain in the joints, seriously affecting the quality of life, and the treatment process will also face certain economic pressure. When it comes to drug treatment, "Febuxostat" in this field is deeply loved by patients due to its excellent curative effect, but it is a bit small!

In fact, the price is not very high. The efficacy of febuxostat produced by Zydus Pharmaceutical Factory in India is the same as that of the original drug, but the price is indeed much lower. The specification is 80mg*30 tablets/box, and its price is about 200$!