非布司他的效果如何？

It is a drug approved in 2009 for the treatment of chronic hyperuricemia. Febuxostat reduces blood uric acid levels by selectively inhibiting xanthine oxidase and reducing uric acid production. It is most suitable for patients with excessive uric acid production. So, what is the therapeutic effect of febuxostat?

Febuxostat is a new type of drug that inhibits uric acid production and has a strong uric acid-lowering effect. The effect of one tablet of febuxostat is about the same as that of three tablets of allopurinol. The occurrence of allergic reactions is significantly reduced, the medication is safe, and there are basically no fatal allergic reactions. And because it is metabolized by the liver, patients with impaired kidney function do not need to adjust their medication. Because it inhibits the production of uric acid from the beginning and does not increase the burden on the kidneys, patients with urinary tract stones can also use it with confidence. Therefore, it is currently the first choice for clinical urate-lowering drugs.

Specific discontinuation time for taking febuxostat:

If gout attacks can be controlled and blood uric acid can be stabilized below the target value for a long time, discontinuation of the drug can be considered under the supervision of a doctor. The statement of lifelong medication is too absolute!

However, if the pain does not occur and the blood uric acid has not reached the target, then the drug must not be stopped and the uric acid-lowering drugs need to be continued to control the blood uric acid to be less than 360 μmol/L, or 300 μmol/L if there is tophi.

In fact, gout is very serious. When treating gout, you must persist and stabilize blood uric acid. When taking medicine, you should be under the guidance of a doctor, and remember not to use medicine indiscriminately.

So, are there any serious side effects of taking febuxostat for a long time?

Because individual differences are different, most patients can usually tolerate it without serious side effects.

The most common adverse reaction of febuxostat during treatment is abnormal liver function. If you find abnormalities during examination, you should consult your doctor whether you need to adjust the medication regimen. Others such as dizziness, nausea, rapid heartbeat, etc. occur less frequently.

As long as everyone can tolerate it after taking it, they should insist on long-term medication.