Long-acting growth hormone subcutaneous injection (somatrogon-ghla): What are the precautions for use?

Long-acting growth hormone subcutaneous injection (Somatrogon-ghla) is a drug specially used to treat growth disorders caused by insufficient secretion of endogenous growth hormone. It is especially suitable for children aged 3 years and above. It effectively promotes bone growth and helps patients achieve normal height development by supplementing the growth hormone that the human body lacks. However, when using this drug, patients and families need to understand and follow a series of precautions to ensure the safety and effectiveness of the drug.

First of all, regarding the storage of medicines, Somatrogon-ghla needs to be protected from light and stored under refrigeration conditions of 2-8°C, and the optimal refrigeration temperature is 4-5°C. Medications should not be stored against the inner wall of the refrigerator or on the refrigerator door to prevent freezing. At the same time, it is strictly prohibited to put sterilized items and syringes in the refrigerator. Medicinal products should be stored in the original carton to protect them from light until first use. After first use, prefilled pens should be stored refrigerated at 2-8°C for up to 28 days, but should not be frozen or shaken.

Before the injection, the patient needs to undergo a series of preparations. The injection time is usually chosen on the same fixed day every week, and there is no specific time limit within the day, but it should be ensured 30-60 minutes before going to bed, or as directed by a doctor. Before injection, the medicine should be taken out of the refrigerator and placed at room temperature for 10-15 minutes to rewarm to avoid discomfort during injection caused by low temperature of the medicine. At the same time, injectors need to wash their hands and choose appropriate injection sites, such as the abdomen, the outside of the middle thigh, the outside of the upper arm, etc. The injection site should be outside the circle with the belly button as the center and a radius of 2 cm; the outer middle thigh should be outside the middle line of the pants, within the side seam, and the middle 1/3 section; the outer third of the upper arm should be under the deltoid muscle. When injecting, avoid areas of pain, skin depressions, subcutaneous nodules, bleeding, congestion and infection.

During the injection, the patient needs to pay attention to injecting the liquid at a constant speed until the injection is completed. Please do not pull out the needle immediately after the injection. The needle should be kept under the skin for at least 10-15 seconds. This ensures that all the medicine enters the subcutaneous tissue and prevents leakage of the medicine from irritating superficial tissues and causing pain. At the same time, in order to avoid the formation of subcutaneous fat nodules and affect the absorption of drugs, patients should rotate injection sites, and the interval between two consecutive injection sites should be 2-3 cm.

Also, when usingDuring Somatrogon-ghla, patients also need to pay attention to their daily living habits. In addition to drug treatment, children's height is also affected by many factors such as diet, nutrition, exercise, sleep, and emotion. Therefore, patients should maintain a balanced diet, ensure adequate intake of milk, eggs, protein foods, vegetables and fruits every day, and eat less snacks and fried junk foods. At the same time, appropriate exercise is also essential, such as skipping rope, playing basketball, etc. The exercise time should be 30-45 minutes, and the heart rate should be maintained at 120-140 beats/minute. In addition, adequate sleep is also an important factor in promoting growth hormone secretion. Patients should try to fall asleep before 22:00 to ensure adequate sleep time.

During the use of Somatrogon-ghla, patients and their families also need to pay close attention to the patient's physical condition and growth. If any discomfort or abnormal reaction occurs, such as pain, redness, swelling, fever at the injection site, etc., you should stop taking the medication immediately and seek medical treatment in time. At the same time, regular physical examination and growth monitoring are also essential so that doctors can adjust treatment plans according to the patient's actual condition.

In summary, long-acting growth hormone subcutaneous injection (Somatrogon-ghla) has significant efficacy in the treatment of pediatric patients with growth disorders caused by insufficient secretion of endogenous growth hormone. However, when using this drug, patients and their families need to understand and follow a series of precautions, including storage of the drug, preparation before injection, precautions during injection, and daily living habits. Only in this way can we ensure the safety and effectiveness of the drug and help patients achieve normal height and development levels.

Reference: https://www.drugs.com/monograph/somatrogon-ghla.html