What kind of medicine does Tolvaptan belong to?

Tolvaptan is a vasopressin V2 receptor antagonist. It works by increasing the amount of water excreted from the body in the form of urine. Expelling fluid from the body helps to increase the sodium content in the blood. Tolvaptan tablets are often used to treat people with heart failure (a condition in which the heart cannot pump enough blood to all parts of the body), syndrome of inappropriate antidiuretic hormone (SIADH) (a condition in which the body produces too much of a certain natural substance, causing the body to retain water), or other conditions.

People withSIADH have an excess of vasopressin, resulting in reduced urine production and blood thinning. The active substance in tolvaptan tablets, tolvaptan, is a "vasopressin-2 receptor antagonist". This means it blocks a receptor that vasopressin normally attaches to. By blocking this receptor, tolvaptan blocks the effects of vasopressin. This increases urine production, reduces the amount of water in the blood, and increases blood sodium levels. Tolvaptan tablets are available in 7.5, 15 and 30 mg.

Tolvaptan tablets have been marketed in China and have entered the scope of Class B medical insurance. The price paid by medical insurance is relatively cheap, but the reimbursement ratio is different in different regions, and the price after reimbursement will be different. Domestic pharmacies or hospitals will sell this drug, and the original drug of tolvaptan tablets is also on the market overseas. There are also generic tolvaptan tablets produced in other countries. The price of Indian pharmaceutical factory production specifications15mg*4 tablets per box is around RMB 800 (the price may fluctuate due to the exchange rate). The ingredients of foreign generic drugs are basically the same as those of domestic and foreign original drugs.