Is the Laotian version of Trametinib effective?

The Laotian version of Trametinib (Trametinib) is a generic drug. Its ingredients and efficacy are basically the same as the original drug Trametinib, but it has different manufacturers, specifications, and prices. The price of the generic version of Trametinib produced by a Lao pharmaceutical factory is around RMB 2,950 per box of 2mg*30 tablets (the price may fluctuate due to exchange rates).

Trametinib is an oral anticancer drug that is a mitogen-activated protein kinase (MEK) inhibitor. It is mainly used to treat malignant tumors such as advanced non-small cell lung cancer, melanoma and unresectable or metastatic solid tumors with BRAF V600E or V600K mutations. In clinical trials, trametinib has shown significant therapeutic effects in certain tumor types. For patients with advanced non-small cell lung cancer, melanoma, and unresectable or metastatic solid tumors with BRAF V600E or V600K mutations, trametinib is often used in combination with other drugs, such as dabrafenib, to improve treatment efficacy.

The original drug of trametinib has been launched in China and has entered the scope of Class B medical insurance, but it may only be purchased by patients who meet the indications of trametinib, such as BRAF V600 mutation-positive unresectable or metastatic melanoma. Its price is around 10,000 to 20,000 yuan. The reimbursement ratio is different in different regions, and the price is also different, making it expensive. The price of the Turkish version of trametinib’s original drug listed overseas is around RMB 7,900 (the price may fluctuate due to exchange rates).