Is baricitinib a biologic?

Baricitinib is not a biologic. Biologics are drugs made by biotechnology and are usually complex organic compounds of proteins or other large molecules. These drugs are often produced by genetic engineering techniques, which involve the use of biological systems, such as cell cultures or genetically modified organisms, to synthesize drug molecules.

In contrast, baricitinib is a small molecule compound and a chemically synthesized drug. It is aJanuskinase inhibitor that modulates immune responses and inflammatory processes by intervening in cell signaling pathways. Baricitinib has a smaller chemical structure and can be administered by the oral route, making it relatively easier to manufacture and distribute than biologics.

Although baricitinib is not a biologic, it is still a prescription drug and needs to be used under a doctor's supervision. Physicians will evaluate the suitability of baricitinib based on the patient's specific situation and needs and provide correct dosage and usage guidance. While using baricitinib, patients should closely follow their doctor's instructions and undergo regular medical examinations and monitoring.

Baricitinib has been launched in China and is included in medical insurance. Patients can purchase it domestically. Due to different medical insurance reimbursement policies in different regions, the reimbursement ratio is also different. The price is about 1200~1600 yuan. For specific prices, please consult the local pharmacy or the medical insurance bureau. Baricitinib has both original and generic drugs abroad. The original drug is mainly Eli Lilly’s original drug, and its price is higher than in China. Generic drugs are mainly Bangladeshi generic drugs, and the price is around 450 yuan. The ingredients of original drugs and generic drugs are basically the same.