Where can I buy the Bangladeshi version of Tofacitinib?

The Bangladeshi version of Tofacitinib (Tofacitinib) is a generic drug. Its drug ingredients and efficacy are basically the same as those of the original drug Tofacitinib , and the specifications are produced by Yaopin International5m The price of g*60 tablets is around 300 RMB, the price of 11mg*30 tablets is around 300 RMB (the price may fluctuate due to the exchange rate), and the price of 5mg*60 tablets produced by Bangladesh Isida Pharmaceutical Factory is around 300 RMB (the price may fluctuate due to the exchange rate).

Tofacitinib was approved by the US Food and Drug Administration in April 2012 for the treatment of rheumatoid arthritis (RA), psoriatic arthritis (PA), ulcerative colitis (UC) and polyarticular juvenile idiopathic arthritis (pcJIA). Tofacitinib is an inhibitor of janus kinase 1 (JAK1) and janus kinase 3 (JAK 3), which means it interferes with the JAK-STAT signaling pathway, which transmits extracellular information into the nucleus and affects DNA transcription. In mouse models of established arthritis, tofacitinib rapidly improves the disease by inhibiting the production of inflammatory mediators and inhibiting STAT1-dependent genes in joint tissues. The efficacy in this disease model is related to the inhibition of JAK1 and JAK3 signaling pathways, indicating that tofacitinib may exert a therapeutic effect by not only inhibiting the JAK3 pathway.

Tofacitinib has been launched in China and has entered the scope of Class B medical insurance. The common specification is tofacitinib citrate tablets . The price paid by medical insurance is relatively cheap, but the reimbursement ratio is different in different regions, and the price after reimbursement will be different. The ingredients of domestic original drugs and foreign generic drugs are basically the same.