The efficacy and role of tocilizumab

Tocilizumab is an immunomodulator that is used to treat a variety of inflammatory diseases. Tocilizumab can bind to and blockIL-6 receptors, thereby reducing the inflammatory response it causes in the body. It is widely used to treat certain autoimmune diseases such as rheumatoid arthritis and giant cell arteritis.

Because tocilizumab interferes with signaling during inflammation, it can reduce the pain, redness, swelling, and joint stiffness associated with inflammation. In people with rheumatoid arthritis, tocilizumab can reduce the progression of joint damage and improve joint function. It is usually used in patients who have not responded to or tolerated other antirheumatic drugs. Tocilizumab can also control the activity of rheumatic diseases such as rheumatoid arthritis by modulating the immune response, reducing joint inflammation and synovial hyperplasia. But tocilizumab may cause some side effects, including an increased risk of infection, gastrointestinal problems, high blood pressure, dyslipidemia, and abnormal liver function. When a patient uses this drug, the doctor may weigh the pros and cons based on individual circumstances and regularly monitor the patient's safety and efficacy.

TocilizumabThe original drug has been launched in China and has been included in the medical insurance. Due to its short time on the market, the second-line treatment of systemic juvenile idiopathic arthritis is still limited to traditional treatments for rheumatoid arthritisDMARDs To treat patients whose disease activity has decreased by less than 50% in 3 to 6 months, Tocilizumab injection can only be used as directed by the doctor. Its price is around RMB 8,600, which is relatively expensive. The price of the European version of tocilizumab original drug available overseas is around around RMB 14,000 (the price may fluctuate due to the exchange rate). The ingredients and efficacy of the two drugs are basically the same. Currently, there are no generic drugs produced and marketed overseas, and patients can choose by themselves.