What are the common side effects of Erdafitinib/Bocco?

Erdafitinib has shown significant results in treating advanced urothelial carcinoma (bladder cancer), but like most targeted drugs, it can cause some side effects. The occurrence and severity of side effects vary from individual to individual, so patients need to be monitored under the guidance of a physician during treatment with BOC. Here are some common side effects:

1. Hyperphosphatemia: This is one of the most common side effects of erdafitinib. Due to FGFR inhibition, BOC may increase phosphorus levels in the body, leading to hyperphosphatemia. Hyperphosphatemia may cause other related symptoms, such as fatigue, muscle twitching, or cardiovascular problems. Therefore, patients will need to have their blood phosphate levels checked regularly during treatment and may need medication or dietary control to manage this side effect.

2. Skin reaction: Boko may cause rash, itching or dry skin and other problems. These skin reactions are usually mild, but in some patients, symptoms may be severe and require topical treatment or pharmacological intervention. Patients should pay attention to skin changes while using the medication and discuss how to manage these symptoms with their doctor.

3. Oral ulcers: Damage to the oral mucosa is also a common side effect of BOC. Patients may experience discomfort such as ulcers in the mouth and dry mouth, which affects eating and quality of life. For this side effect, doctors often recommend that patients use anti-inflammatory medications or mouthwash to relieve it.

4. Fatigue and weakness: As an anti-cancer drug, Boco sometimes causes patients to feel fatigue or weakness. This is because drugs that inhibit the growth of tumor cells may also affect the function of normal cells. Patients should avoid overexertion, ensure adequate rest, and adjust the treatment plan according to the doctor's recommendations if necessary.

In addition to these common side effects, BOC may also cause some rare but serious side effects, such as liver function damage, kidney function damage, etc. Therefore, patients need to regularly check their liver and kidney functions during treatment to ensure that the drugs will not have adverse effects on these organs.

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