How to deal with the side effects of sotorasib?

is a targeted therapy drug that is mainly used for the treatment of specific types of cancer. Although it shows significant efficacy in controlling disease progression, like most drugs, it may also be accompanied by certain side effects. Correct identification and appropriate management of these side effects are critical to ensuring patient quality of life and continuity of treatment.

Methods for dealing with side effects

1. Gastrointestinal reactions: Symptoms: Nausea, vomiting, diarrhea and indigestion are common gastrointestinal side effects. Patients are advised to maintain adequate fluid intake, avoid greasy and spicy foods, and adopt a diet of multiple small meals. Your doctor may prescribe anti-nausea medications or adjust your dosage to reduce these symptoms.

2. Skin reaction: Symptoms include rash, dryness, itching or nail changes. Keep your skin clean and dry, and use mild, non-irritating skin care products. Severe rashes may require topical or oral medication and should seek prompt medical attention.

3. Fatigue: If you feel persistently tired or weak, you should arrange a reasonable rest and perform appropriate light to moderate physical activities, such as walking, to improve your physical fitness. Keep your nutrition balanced and seek help from your doctor to make adjustments if necessary.

4. Hematological side effects: may include leukopenia, anemia or thrombocytopenia. Regular blood tests are recommended, and based on the test results, your doctor may adjust the medication dose or provide supportive care, such as blood transfusions.

5. Abnormal liver function: There may be no obvious symptoms, but elevated liver enzymes can be found through blood tests. It is recommended to monitor liver function regularly and avoid alcohol and drugs that may damage the liver. In severe cases, your doctor may adjust the medication or temporarily stop it.

6. High blood pressure: Symptoms include headache, blurred vision, palpitations, etc. Blood pressure should be monitored regularly and antihypertensive drugs should be taken if necessary. Lifestyle adjustments, such as a low-salt diet and moderate exercise, can also help control blood pressure.

If any side effects occur during treatment with sotoraxib, you should inform your doctor immediately and do not stop the medication or adjust the dose on your own. Everyone's physique and reaction are different, and doctors will develop personalized management plans based on specific circumstances. During the medication period, patients should be reviewed regularly, visit the doctor regularly, conduct necessary physical examinations and laboratory tests, and adjust the treatment plan in a timely manner.