那他霉素滴眼液有替代品吗?
There are alternatives to natamycin eye drops. Natamycin eye drops can be replaced by other antifungal drugs, such as tobramycin eye drops, fluconazole eye drops, etc. If patients in need cannot choose natamycin eye drops for treatment, they can choose other drug treatments under the guidance of a doctor.
Natamycin Eye Drops is a macrolide polyene antibiotic with broad-spectrum antifungal activity and low toxicity. It is resistant to a variety of yeasts and filamentous fungi, such as Cephalosporium, Fusarium, Candida, Aspergillus, and Penicillium. It is mainly used clinically for fungal keratitis, fungal blepharitis, fungal conjunctivitis, fungal corneal ulcers, etc.
tobramycin eye drops
Tobramycin is a powerful and effective aminoglycoside approved for use in complicated infections and reinfections, primarily against Gram-negative bacteria such as Pseudomonas aeruginosa, Escherichia coli, Proteus, Klebsiella, Enterobacter, Serratia, Providencia and Citrobacter.
Due to the broad spectrum of activity of tobramycin, tobramycin eye drops have been shown to be useful in the control of superficial and deep infections of the eye and ocular appendages (i.e., ophthalmitis, conjunctivitis, keratitis, and endophthalmitis) and are characterized by a rapid bactericidal effect and are even effective against multidrug-resistant organisms (MDR).
However, it is important to note that because tobramycin is associated with neuromuscular blockade and has ototoxic and nephrotoxic effects, care must be taken to minimize toxicity by monitoring patients receiving systemic tobramycin.
fluconazole eye drops
Fluconazole is a new triazole derivative. Fluconazole eye drops can prevent the growth and reproduction of fungi by inhibiting the cell wall synthesis of fungi. It is clinically suitable for the treatment of fungal conjunctivitis, fungal conjunctivitis and other ocular fungal infections caused by Aspergillus fumigatus, Candida albicans, Cryptococcus and Coccidioides.
When using eye drops, patients should shake the bottle fully before use. When instilling eye drops, the eye drops should be placed vertically, and the mouth of the bottle should not come into contact with the eyes. After use, the bottle cap should be tightened to avoid contamination of the liquid. It is prohibited for patients who are allergic to drug ingredients, otherwise discomfort symptoms such as rash may occur.
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