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氢化可的松片(hydrocortisone)主要治疗什么病症？
(hydrocortisone) The main ingredient is hydrocortisone acetate, which is mainly used for replacement therapy in the treatment of adrenal insufficiency and congenital adrenal hyperplasia. During the course of corticosteroid treatment, attention should be paid to monitoring blood 17-hydroxyprogesterone or urinary 17-ketosteroids. For salt-losing patients, blood potassium, sodium, chloride, etc. should also be monitored. Adjust the dosage of glucocorticoids. In children under stressful situations (such as infection, overwork, surgery, etc.) or during adolescence, the dosage of glucocorticoids should be increased by 1.5-2 times than usual.
In other words, the pharmacology and toxicology of hydrocortisone acetate tablets are: (1) Anti-inflammatory effect: glucocorticoids reduce and prevent tissue responses to inflammation, thereby reducing the manifestations of inflammation. (2) Immunosuppressive effect: Prevent or inhibit cell-mediated immune responses, delayed allergic reactions, and reduce the expansion of primary immune responses. (3) Anti-toxic and anti-shock effects: Glucocorticoids can counteract the stimulating response of bacterial endotoxins to the body, reduce cell damage, and play a role in protecting the body.
(hydrocortisone) can be rapidly absorbed from the digestive tract. The blood concentration reaches its peak in about 1 hour. Its biological T1/2 is about 100 minutes. More than 90% of the blood content is combined with plasma proteins. Most of the metabolites are conjugated into glucuronide esters, and a very small amount is excreted unchanged in the urine. The ointment of this product can be absorbed through the skin, especially in damaged skin areas.Currently, hydrocortisone tablets (hydrocortisone) are not on the market in mainland China. According to Medical Travel, the Hong Kong version of hydrocortisone tablets is about $1,000. Since exchange rates fluctuate and prices are not fixed, please consult Medical Travel for specific prices.
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