How much does a box of Veozah, the world's first NK3 receptor antagonist non-hormonal drug, cost?

The world's first NK3 receptor antagonist non-hormonal drug is available in 45mg*30 tablets, with a reference price of approximately $20,655.

As of January 2024, Veozah is not on the domestic market, and patients can only choose to go abroad to purchase it themselves or trust domestic and overseas medical service institutions to help them purchase Veozah.

About Veozah

Veozah is an oral drug that selectively targets the neurokinin 3 (NK3) receptor and is indicated for the treatment of moderate to severe vasomotor syndrome or hot flashes (VMS) caused by menopause.

1. Mechanism of action: Fezonatan tablets block the binding of NK3 to kisspeptin/neurokinin/dynorphin (KNDy) nerves by binding to NK3 receptors, thereby regulating the nerve activity of the brain's temperature regulation center (hypothalamus). This regulation plays a role in reducing the frequency and severity of moderate to severe VMS associated with menopause.

2. The first NK3 receptor antagonist: Fezonatan tablets are the first NK3 receptor antagonist approved by the FDA for menopausal VMS. This new treatment option provides a non-hormonal treatment option for those with moderate to severe VMS symptoms.

3. The world's first non-hormonal treatment drug: Fezonatan tablets are also the world's first non-hormonal treatment drug for VMS that adopts this new mechanism of action. This new treatment option provides an alternative for menopausal women who wish to avoid hormone replacement therapy.

Veozah (Veozah)

Veozah showed significant efficacy in two pivotal confirmatory clinical trials (SKYLIGHT 1 and 2), reducing the frequency and severity of moderate to severe VMS compared to placebo, and these results were statistically significant.

In addition, the long-term safety study (SKYLIGHT 4) showed that no risk of endometrial hyperplasia or cancer was observed during the use of Fezonatan Tablets. Common adverse drug reactions include abdominal pain, diarrhea, etc., but the incidence is low. In addition, it should be noted that Fezonatan tablets may also cause increased liver aminotransferases or liver damage, so liver function needs to be monitored.

In summary, Fezonatant tablets can rapidly reduce the frequency and severity of VMS by targeting the brain circuitry that regulates body temperature. It is considered to be as effective as hormone replacement therapy (HRT) and can show results within a week. For those female VMS patients who are intolerant to hormone replacement therapy, Fezonatan tablets provide a treatment option with a new mechanism.

Price and purchase of Veozah

The world’s first NK3 receptor antagonist non-hormonal drug Veozah has a specification of 45mg*30 tablets, with a reference price of about $20,655. As of January 2024, Veozah is not on the market in China, and patients can only choose to go abroad to purchase it themselves or trust domestic and overseas medical service organizations (such as Medical Companion Travel) to help them purchase Veozah.

The purchase process may vary from different medical service institutions, but the general steps are as follows:

1. Online consultation: Fill in the relevant information and conduct online consultation through the website or application of the medical service institution. You may be asked to provide your medical records or prescriptions to obtain medications.

2. Prescription: Doctors at medical service institutions will evaluate your condition and issue a prescription. Please make sure you provide accurate and complete medical information.

3. Order and payment: According to the doctor's prescription, you can place an order for the medicine and choose the appropriate payment method. Some medical service institutions accept payment methods such as credit cards and Alipay.

4. Mail delivery: Once you complete the payment, the medicine will be delivered to your address via mail service. Please note that delivery times may vary by country and region.

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