依普利酮可以长期服用吗？

Planep, produced by India's Lupine Pharmaceuticals, is a new type of selective aldosterone receptor antagonist that only acts on mineralocorticoid receptors and does not act on androgen and progesterone receptors. Eplerenone also has a good antihypertensive effect in patients with essential hypertension with low renin levels for whom angiotensin-converting enzyme inhibitors and angiotensin II receptor inhibitors are not effective. Eplerenone can significantly reduce the ultrafiltration effect of glomeruli and reduce albuminuria in patients with hypertension. This renal protective effect is more obvious for patients with hypertension and diabetes.

1. For congestive heart failure after acute myocardial infarction: The recommended dose of eplerenone (Planep) from India's Lupine Pharmaceuticals is 50 mg/time, once/day. The initial dose should be 25 mg/time, once/day, and within 4 weeks, the dose should be gradually increased to 50 mg/time, once/day under the conditions tolerated by the patient within 4 weeks.

2. Anti-hypertensive: Eplerenone (Planep) from India's Lupine Pharmaceuticals can be used alone or in combination with other anti-hypertensive drugs. The recommended initial dose for use alone is 50mg/time, once/day. Obvious antihypertensive effects appear within four weeks of taking the drug. If the antihypertensive effect is not obvious, it can be increased to 50mg/time, 2 times/day. Higher dosages are not recommended, otherwise there is an increased risk of adverse reactions such as hyperkalemia.

Can Indian Lupine Pharmaceuticals take eplerenone for a long time?

Whether Indian Lupine Pharmaceuticals needs to be taken for a long time depends on the patient's own situation. It is recommended that patients use it under the guidance of a doctor. If the patient takes the drug Eplerenone from India Lupine Pharmaceuticals, which has obvious antihypertensive effect, it can be used continuously.

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