依普利酮能长期用吗？

(eplerenone, Inspra) is the first selective aldosterone receptor antagonist. It has been used to treat hypertension and left ventricular dysfunction after acute myocardial infarction. It can effectively lower blood pressure, improve cardiac function, and reduce myocardial damage.

  Can eplerenone be used long-term?

Eplerenone was first launched in the United States in 2002 for the treatment of hypertension, heart failure and myocardial infarction. It has definite efficacy in treating hypertension, heart failure and myocardial infarction, has fewer adverse reactions and is well tolerated. Eplerenone can be used until drug resistance develops. Eplerenone (Inspra) takes a certain period of time to achieve the best effect of lowering blood pressure. It is also very safe when used in combination with other antihypertensive drugs. Therefore, it is recommended that when taking eplerenone (Inspra) early, it can be combined with other antihypertensive drugs to control blood pressure. After eplerenone reaches its peak effect, it can be used alone.

Studies have shown that eplerenone (Inspra) can cause a sustained increase in plasma renin and serum aldosterone, and at the same time block the feedback regulatory effect of aldosterone. However, the increase in plasma renin activity and the increase in systemic circulation aldosterone levels will not offset the blood pressure control effect of eplerenone (Inspra). Eplerenone and spironolactone work on the same principle. Long-term use of spironolactone can cause endocrine disorders, while eplerenone (Inspra) is well tolerated and has the advantage of less side effects and avoids the side effects of endocrine disorders.

The above is the introduction about (eplerenone), I hope it can help everyone. If patients have other questions about the drug (such as drug price, purchasing channels, etc.), they can consult the medical companion travel service.  

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