降压药依普利酮去哪里买

It is a new type of selective aldosterone receptor antagonist. For severe hypertension that cannot be controlled by a combination of multiple antihypertensive drugs, the addition of eplerenone can significantly reduce blood pressure, especially the decrease in systolic blood pressure is more significant. Combined treatment with angiotensin-converting enzyme inhibitors (ACEI) and beta-blockers can improve patients' quality of life and reduce mortality in severe heart failure and myocardial infarction.

Treatment of post-acute myocardial infarction heart failure combined with standard therapeutic drugs can reduce overall mortality in the treatment group by 15% (P=0.008);

Eplerenone and enalapril are equally effective in reversing left ventricular hypertrophy and hypertension, with fewer cough side effects, and the combined effect is more obvious;

There are few adverse reactions. Except for the adverse reactions of elevated blood potassium, other adverse reactions are no different from the placebo group; there are almost no sex hormone-related side effects of spironolactone.

The FDA (U.S. Food and Drug Administration) has approved eplerenone for use in stable patients with left ventricular systolic dysfunction (ejection fraction <40%) and congestive heart failure after acute myocardial infarction (MI) to improve survival rates. Eplerenone is the first aldosterone receptor blocker approved for this indication. The FDA's approval was based on the results of the EPHESUS (Eplerenone Efficacy and Survival Study in Heart Failure After Acute Myocardial Infarction) trial. In patients with heart failure after myocardial infarction, eplerenone plus standard care reduced mortality by 15% compared with placebo and standard care (ACE inhibitors and beta-blockers). The main adverse reactions of eplerenone include: cough, diarrhea, abdominal pain, angina, myocardial infarction, proteinuria, headache, dizziness, fatigue, flu-like symptoms, etc. Other adverse reactions of eplerenone include: gynecomastia, abnormal vaginal bleeding; increases (serum potassium, triglycerides, cholesterol, alanine aminotransferase, γ-glutamyl transferase, creatinine, uric acid levels), and decreased serum sodium levels.

According to Medical Travel, we learned that eplerenone is not on the market in China, and the original drug is extremely expensive. Fortunately, there is also an Indian pharmaceutical product with a specification of 50mg/100 tablets and a price of about $500. Since exchange rates fluctuate and prices are not fixed, please consult Medical Travel for specific prices and drug purchase procedures.

Recommended related hot articles: /newsDetail/79991.html