日本高级降压药依普利酮效果怎么样

(eplerenone) is a new type of selective aldosterone receptor antagonist. In 2002, eplerenone was approved in the United States for the treatment of patients with hypertension. Eplerenone can improve the quality of life of patients with left ventricular dysfunction (ejection fraction ≤ 40%). Clinical trials have proven that eplerenone can also be used for congestive heart failure after acute myocardial infarction.

How effective is the Japanese advanced antihypertensive drug eplerenone?

Eplerenone is effective in treating patients with stage 1 and stage 2 hypertension and has similar effectiveness and magnitude in reducing systolic and diastolic blood pressure as enalapril. Eplerenone also has a good antihypertensive effect in patients with essential hypertension with low renin levels who do not respond well to angiotensin-converting enzyme inhibitors and angiotensin receptor inhibitors. It also has a good antihypertensive effect on simple systolic hypertension, and has a good antihypertensive effect on diet-induced obesity-related hypertension. In addition, eplerenone can significantly reduce the ultrafiltration effect of glomeruli and reduce albuminuria in patients with hypertension. This renal protective effect is more obvious for hypertensive patients with diabetes.

Advantages of eplerenone: It is a good medicine for the treatment of hypertension. It is also used as a medicine for myocardial ischemia and chronic myocardial insufficiency. This medicine has a protective effect on the liver, heart disease, and kidneys without damaging the organs. Eplerenone (Planep) can promote urination without losing potassium.

Taking (eplerenone) for treatment will also produce certain side effects or adverse reactions, including: hyperkalemia/hypertriglyceridemia/dizziness/fatigue/hyponatremia/proteinuria/hypercholesterolemia/abdominal pain/increased serum creatinine/cough/angioedema/increased liver enzymes/rash, etc. Therefore, patients must go to the hospital for detailed examination before receiving this drug for treatment, and use the drug strictly according to the doctor's diagnosis and treatment recommendations.

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