依普利酮在国内有卖吗

(Eplerenone) is a new type of selective aldosterone receptor blocker that can effectively control hypertension, reduce damage to target organs such as the heart, brain and kidneys, and improve microalbuminuria in patients with type 2 diabetes. Eplerenone is a new type of selective aldosterone receptor antagonist. It was approved for clinical use by the State Food and Drug Administration in 2002. The pure product is white or off-white crystal. Its antagonistic effect on aldosterone is stronger than that of spironolactone. It has extremely low affinity for androgen and progesterone receptors and has few adverse reactions. It has definite efficacy in the treatment of hypertension, heart failure and myocardial infarction. It has fewer adverse reactions and good tolerance. It is a good alternative drug to spironolactone.

For severe hypertension that cannot be controlled by a combination of multiple antihypertensive drugs, the addition of eplerenone can significantly reduce blood pressure, especially the decrease in systolic blood pressure is more significant. Combined treatment with angiotensin-converting enzyme inhibitors (ACEI) and beta-blockers can improve patients' quality of life and reduce mortality in severe heart failure and myocardial infarction. The FDA has approved eplerenone (Inspra - Pfizer) for use in stable patients with left ventricular systolic dysfunction (ejection fraction <40%) and congestive heart failure after acute myocardial infarction (MI) to improve survival. Eplerenone is the first aldosterone receptor blocker approved for this indication.

Is it sold in the country? At present, eplerenone is not on the market in China. It is only sold in the United States and Japan. It is understood that the price of the original drug of eplerenone in the United States is relatively high. The specifications are 50mg-30 tablets/box, and the price is about 124.09 US dollars. The price is very expensive, but fortunately, India also has a generic version of this product, which has the same efficacy and is affordable. According to Medical Travel, we learned that the price of eplerenone 50mg 100 tablets from India's Lupine Pharmaceuticals is about $500. Since exchange rates fluctuate and prices are not fixed, please consult Medical Travel for specific prices.