Inspra售价是多少呢？

It is a new highly selective aldosterone receptor blocker that can be used for the treatment of heart failure, hypertension, and coronary heart disease. With the continuous progress of research, the scope of clinical application of Inspra is constantly being expanded, and its status in the field of cardiovascular disease treatment is also constantly improving.

EPHESUS研究的亚组分析也显示对高血压患者来说Inspra对减少总死亡率的作用更加明显。 A comparative study on the efficacy and tolerability of 499 patients with grade 1 or 2 hypertension who were randomized to receive enalapril or Inspra showed that at 6 months, enalapril was as effective as Inspra in reducing systolic blood pressure (Inspra decreased by 14.5 mmHg; Enalapril decreased by 12.7 mmHg: P=0.199) and diastolic blood pressure (Inspra decreased by 11.2 mmHg; Enalapril decreased by 11.3 mm Hg; P=0.910). After 12 months, the two groups were also similar (eplerenone-16.5/-13.3mmHg; enalapril-14.8/-14.1mmHg, P values ​​0.251 and 0.331 respectively).

The rates of withdrawal due to adverse events (7.9% for eplerenone and 9.3% for enalapril at 6 months) and treatment failure were also equal (23.3% for eplerenone and 22.8% for enalapril at 6 months). About 2/3 of the patients in each group achieved normal blood pressure at 6 months with the above single treatment.在Inspra组，血压的下降不依赖肾素水平这与依那普利不一样。 Both groups can reduce proteinuria above normal levels, but the Inspra group is more obvious (-61.5% vs -25.7%; P=0.01); Inspra can improve the quality of life of patients with left ventricular dysfunction (ejection fraction ≤ 40%), and clinical trials have proven that Inspra can also be used for congestive heart failure after acute myocardial infarction.

So how much does Inspra cost? 

Inspra was developed by Pfizer of the United States and first launched in the United States in 2002. It is mainly used clinically to treat hypertension. In 2003, it was approved by the FDA for the treatment of heart failure after acute myocardial infarction. Inspra has not yet been launched in my country, so we have no way of knowing the domestic price. Medical Travel learned that the price of Inspra 25mg-30 tablets/box in the United States in 2019 was around US$118.71. However, the price of Inspra 50mg*100 tablets from India's Lupine Pharmaceuticals is around RMB 500, which is very cheap. Patients can choose to buy it in person at the place of origin or obtain it through regular domestic medical institutions.小编不建议患者选择代购，某些代购商家的药品来源无法保证真实性，这样会耽误患者的后续治疗。