eplerenone怎么买？

Binds to mineralocorticoid receptors, thereby blocking the binding of aldosterone, a component of the renin-angiotensin-aldosterone system (RAAS). Aldosterone synthesis occurs primarily in the adrenal gland and is regulated by multiple factors, including angiotensin II and non-RAAS mediators such as adrenocorticotropic hormone (ACTH) and potassium. Aldosterone binds to mineralocorticoid receptors in epithelial tissues (such as the kidneys) and non-epithelial tissues (such as the heart, blood vessels, and brain) and increases blood pressure by inducing sodium reabsorption and possibly other mechanisms.

eplerenone adverse reactions

>10%

Endocrinology and Metabolism: Hyperkalemia ([Heart failure, post-myocardial infarction: >5.5 meq/L: 16%; ≥6 meq/L: 6%], [Hypertension, >5.5 meq/L: 400 mg: 9%; doses ≤200 mg: ≤1%]), hypertriglyceridemia (1%-15%; dose related).

1%-10%

Central nervous system: dizziness (3%), fatigue (2%)

Endocrinology and Metabolism: Hyponatremia (2%; dose-related), proteinuria (1%), gynecomastia (≤1%), hypercholesterolemia (≤1%)

Gastrointestinal tract: diarrhea (2%), abdominal pain (1%)

Genitourinary system: abnormal vaginal bleeding (≤2%), breast pain (males: ≤1%)

Kidney: elevated serum creatinine (heart failure, post-myocardial infarction: 6%)

Respiratory system: cough (2%), flu-like symptoms (2%)

<1% post-marketing or case reports: angioedema, increased blood urea nitrogen, increased liver enzymes, increased uric acid, rash.

The therapeutic effect of eplerenone is so effective that patients who need to purchase it can find medical companions from overseas medical institutions in China for consultation.