依普利酮纳入医保了吗？

, Product name: Planep. Eplerenone is a new, highly selective aldosterone receptor blocker that can be used for the treatment of heart failure, hypertension, and coronary heart disease. Eplerenone was developed by Pfizer and first launched in the United States in 2002.

Eplerenone is mainly used to treat heart failure after primary hypertension and myocardial infarction. Its mechanism of action is to bind to aldosterone receptors and block aldosterone in the renin-angiotensin-aldosterone system (RAAS), thereby lowering blood pressure.

Eplerenone can be used alone or in combination with other antihypertensive drugs to treat hypertension. The recommended dose for adults is the initial dose: 50 mg orally once daily. Maintenance dose: 50 mg orally, 1-2 times daily. Maximum dose: 100 mg/day. Obvious antihypertensive effects appear within four weeks of taking the drug. Patients whose blood pressure responds inadequately to the initial dose may be increased to 50 mg twice daily.

In patients with low-renin hypertension, the antihypertensive effect of eplerenone is better than that of losartan. For patients with hypertension who are poorly controlled by ARB alone, adding eplerenone (50~100 mg·d) for 8 weeks can further enhance the effect of reducing systolic blood pressure (SBP) and diastolic blood pressure (DBP). For elderly patients with hypertension who are poorly controlled by ACEI or ARB, the addition of low-dose (25-50 mg/d, average 37.5 mg) eplerenone can effectively reduce the average 24-hour systolic blood pressure (SBP) and diastolic blood pressure (DBP).

Eplerenone is not currently on the market in my country, so it cannot be reimbursed by medical insurance. It is understood that eplerenone is available in Taiwan and Hong Kong, but it is not convenient to buy eplerenone as a prescription drug, and domestic medical insurance cannot be used in Hong Kong and Taiwan. The price of the original drug is usually relatively high, so it is not cost-effective to buy it in Hong Kong and Taiwan.

The most economical way is actually to choose to buy generic drugs produced in India. The efficacy and method of taking the generic drugs are basically the same as the original drugs. However, there are no high research and development costs, so the pricing is relatively low. The price of 50mg*100 tablets from India's Luping Pharmaceutical is about $500 in RMB.