阿托伐他汀作用与功效

The role and efficacy of atorvastatin: suitable for hypercholesterolemia and coronary heart disease.

1. Hypercholesterolemia:

In patients with primary hypercholesterolemia, including familial hypercholesterolemia (heterozygous type) or mixed hyperlipidemia (equivalent to types IIa and IIb in the Fredrickson classification), if the effects of dietary therapy and other non-drug treatments are unsatisfactory, atorvastatin can be used to treat elevated total cholesterol, elevated low-density lipoprotein cholesterol, elevated apolipoprotein B, and elevated triglycerides.

In patients with homozygous familial hypercholesterolemia, atorvastatin can be used in combination with other lipid-lowering therapies (such as LDL plasma dialysis) or alone (when no other treatment options are available) to reduce total cholesterol and low-density lipoprotein cholesterol.

2. Coronary heart disease:

In patients with coronary heart disease or coronary heart disease-related risks (such as diabetes, symptomatic atherosclerotic disease, etc.) combined with hypercholesterolemia or mixed dyslipidemia, atorvastatin is suitable for: reducing the risk of non-fatal myocardial infarction, reducing the risk of fatal and non-fatal stroke, reducing the risk of revascularization, reducing the risk of hospitalization due to congestive heart failure, and reducing the risk of angina pectoris.

In addition, the efficacy and safety have been confirmed in more than 400 clinical trials and 230 million patient-years of clinical medication experience. Numerous clinical practices have consistently confirmed that atorvastatin 10-80 mg can effectively reduce low-density lipoprotein cholesterol (LDL-C). For patients with coronary heart disease, ischemic stroke, diabetes, hypertension and other high-risk cardiovascular disease patients, atorvastatin has been proven to reduce major cardiovascular events and has been proven to be safe.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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