索格列净的用法用量
Sogliflozin is an oral dual inhibitor of sodium-glucose cotransporters type 1 and type 2 (SGLT1 and SGLT2). It is not yet on the market in China. Its recommended starting dose is 200 mg once a day, which can be adjusted to 400 mg based on tolerance. This medicine should be swallowed whole and avoid cutting or chewing. If the dose is missed for more than 6 hours, skip the dose. Common side effects include hypoglycemia, urinary system infection, etc. Special groups such as those with renal insufficiency need to adjust the dosage.
Sogliflozin usage and dosage
The correct usage and dosage adjustment are crucial to the therapeutic effect. Patients should strictly follow the doctor's instructions and avoid adjusting the dosage or changing the way of taking the medicine on their own.
Recommended starting dose
The recommended starting dose of INPEFA is 200 mg, administered orally once daily. Medication should be taken within 1 hour before the first meal of the day to optimize drug absorption.
Dose adjustment plan
After at least 2 weeks of initial treatment, the doctor will consider increasing the dose to 400 mg once daily based on the patient's tolerance. If adverse reactions occur, the dose may be adjusted back to 200 mg.
Precautions for taking the medicine
The tablets must be swallowed whole and should not be cut, crushed or chewed. If you miss a dose for more than 6 hours, you should skip the dose and continue taking the medicine as originally planned the next day.
Correctly mastering the dosage of sogliflozin can improve the therapeutic effect and reduce the risk of adverse reactions. Patients should have regular follow-up visits and timely feedback on their medication status.
Side effects of soxgliflozin
Understanding the possible side effects of soxgliflozin can help patients detect abnormalities in time and take appropriate measures.
Common adverse reactions
Using soxgliflozin may cause symptoms of hypoglycemia, such as dizziness, sweating, palpitations, etc. Some patients report urinary tract infections or genital fungal infections.
Serious adverse reactions
In rare cases, symptoms of ketoacidosis may occur, including difficulty breathing, nausea and vomiting, confusion, etc. Dehydration-related symptoms such as extreme thirst and reduced urine output also need to be alert.
Side Effect Management
Dose adjustment may be considered when mild side effects occur. Severe reactions should stop the medication immediately and seek medical attention. Regular monitoring of blood sugar and kidney function can help detect problems early.
Patients should fully understand the side effects of soxgliflozin and remain alert during medication, but there is no need to worry excessively. Timely communication with doctors can effectively control risks.
Sogliflozin medication for special groups
Different groups of people have different metabolism and reactions to sogliflozin, and individualized medication plans are required.
Patients with hepatic impairment
No dose adjustment is required in patients with mild hepatic impairment. The safety and efficacy of INPEFA (sogliflozin) in patients with moderate or severe hepatic impairment have not been established.
Elderly patients
It is not recommended to change the INPEFA (sogliflozin) dose based on age.
Pregnant and lactating women
The safety of use during pregnancy has not been established and its use is generally not recommended. Breastfeeding women should weigh the pros and cons and suspend breastfeeding if necessary.
Special groups need to be more cautious when using sogliflozin. Doctors will develop personalized treatment plans based on specific circumstances, and patients should actively cooperate with monitoring work.
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