维利西呱有停药反应吗？

There were no withdrawal reactions. There is no description of discontinuation reactions in the drug instructions for Vericiguat. This drug must be used continuously unless there are special circumstances. Patients should stop taking medication, increase or decrease dosage, etc. under the guidance of a doctor, and should not increase or decrease dosage of medication without permission.

Drug introduction

Vericiguat is an orally available stimulator of soluble guanylate cyclase (sGC), the key enzyme in nitric oxide-induced vascular relaxation, for use in patients with chronic heart failure to reduce the risk of death and hospitalization.

medicine

Vericiguat has fewer side effects, with common side effects being hypotension and anemia. If a patient develops hypotension or anemia during medication, he or she should pay attention to monitoring blood pressure and blood routine to understand their own situation and avoid drug side effects that may affect their health.

Contraindications of Vericiguat

1. Vericiguat is contraindicated in patients who use other soluble ornitrate cyclase (sGC) stimulators at the same time to avoid drug interactions, affect the therapeutic effect, and cause adverse reactions. In addition, it is not recommended that patients use PDE-5 inhibitors during medication to avoid hypotension.

2. Pregnant women are prohibited from taking Vericiguat during pregnancy to avoid miscarriage, fetal malformation and other hazards, which may have an impact on the fetus and the pregnant woman herself.

Medications for patients with heart failure

1. Patients should pay attention to rest during the medication period, avoid fatigue, avoid staying up late, eat a light and nutritious diet, low-salt and low-fat diet, and avoid eating spicy and irritating foods such as peppers and Malatang.

2. If the patient has difficulty swallowing, the tablets can be crushed and mixed with water.

3. After the condition is stable, patients can exercise appropriately during medication, such as walking, doing Tai Chi, Baduanjin, etc. They should keep a happy mood during medication and avoid excessive fluctuations.

4. Patients should strictly follow the doctor's instructions when taking medication and do not overdose. The maximum daily dose is 10 mg to avoid adverse reactions such as hypotension caused by excessive medication.

5. Patients with mild to moderate liver function impairment do not need to adjust the drug dosage. In addition, Veliciguat may affect the fetus. Therefore, it is recommended that women of childbearing age use contraception within one month of stopping the drug.

6. Since Vericiguat will be secreted into breast milk, lactating women should stop breastfeeding during the medication to avoid serious adverse reactions to the baby.

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