How should veliciguat be used? What are the adverse reactions of long-term use of Vericiguat

Vericiguat is the first new drug approved by the US FDA in 2021. It is the first chronic heart failure treatment approved for patients who are hospitalized for heart failure or require IV diuretics. VICTORIA's phase 3 clinical trial results show that vericiguat can reduce the risk of patients' composite endpoint of hospitalization for heart failure and death from cardiovascular causes, and can have a positive effect on the patient's condition, with significant therapeutic effects. How should it be used? What are the adverse effects of long-term use of Vericiguat?

How to use Vericiguat

The recommended starting dose of vericiguat is 2.5 mg orally daily with food. The dose of veliciguat should be doubled approximately every 2 weeks to achieve the patient's target maintenance dose of 10 mg per day. For patients who have difficulty swallowing, the medicine can be crushed and mixed with water. Due to the different disease progression, personal constitution and drug tolerance of each patient, the dosage and treatment time of vericiguat treatment will also be different. The actual dosage of vericiguat can be determined according to the patient's disease stage and drug tolerance. Patients should strictly follow the doctor's instructions when taking medication, so as to obtain better therapeutic effects.

Vericiguat adverse reactions

Adverse reactions of Vericiguat include: hypotension, anemia, etc. Because each patient's disease progresses differently, patients may experience side effects after treatment with vericiguat, the severity of the side effects, and the time of occurrence may also vary. If patients experience serious side effects while receiving vericiguat, they should go to the hospital immediately and receive formal treatment from a professional doctor. After adverse reactions occur, patients should not blindly use other drug treatments to avoid causing more adverse reactions and affecting their condition.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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