氯法齐明治疗麻风疗效怎么样？有什么需要注意的？

The first choice drug for the treatment of neoplastic leprosy is antibacterial drugs, which should usually be used in combination with dapsone; combined with rifampicin or ethionamide for the treatment of infections caused by strains resistant to sulfone drugs; it can also be used for erythematous nodular leprosy reactions and acute leprosy reactions caused by other drugs.

So, how effective is clofazimine in treating leprosy?

Clofazimine has both preventive and therapeutic effects on leprosy erythema nodosum. The incidence and severity of leprosy erythema nodosum in tumor-type patients treated with clofazimine are significantly lower than those treated with DDS. For long-term glucocorticoid-dependent erythema nodosum leprosy, glucocorticoids can be gradually withdrawn after treatment with clofazimine. In addition, clofazimine is also effective in treating neuritis caused by type I leprosy. Clofazimine soft capsules can be used to treat tumor-type leprosy, erythematous nodular leprosy, acute leprosy caused by other drugs, and anti-viral strain infections. In daily life, patients should follow the doctor's instructions and take medication. During the medication process, they should not eat too spicy food, eat a light diet, and should not catch cold.

So, what should you pay attention to during clofazimine treatment?

Clofazimine should be taken with food or milk; people with a history of gastrointestinal disease or liver function impairment and those who are intolerant to this product should use it with caution; treatment for multiple bacilli (borderline, borderline-tumor and neoplastic leprosy) leprosy should last for more than 2 years, or even lifelong administration; pregnant women should avoid using this product, and lactating women should not use this product; daily When the dose exceeds 100 mg, close observation should be made, and the course of treatment should be as short as possible; in case of overdose, vomiting, gastric lavage, catharsis, and symptomatic and supportive treatment should be given if necessary; when treating multiple bacillary leprosy with erythematous nodule lepromatous reaction, if there are ominous signs of nerve damage or skin ulcers, this product can be combined with adrenocortical hormones.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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