How many days should you take Trametinib?

Trametinib (Trametinib) must be started and supervised by a doctor experienced in using cancer drugs. Currently only available by prescription, these drugs can only be used if there is a BRAF gene change in the cancer. Before starting treatment, patients need to have melanoma and non-small cell lung cancer cells tested to check for this genetic change.

Trametinib is available in tablet sizes of 0.5 mg and 2 mg, as well as oral solution formulations. The dose of Trametinib is 2 mg. It should be taken once a day on an empty stomach at least 1 hour before or 2 hours after meals. As long as the patient benefits from it, they can continue to use Trametinib. After surgery for patients with advanced melanoma, treatment usually continues for 12 months unless the disease returns. If certain side effects occur, treatment may need to be interrupted or stopped, or the dose of trametinib may need to be reduced.

The original drug of trametinib has been launched in China and has entered the scope of Class B medical insurance, but it may only be purchased by patients who meet the indications of trametinib, such as BRAF V600 mutation-positive unresectable or metastatic melanoma. Its price is around 10,000 to 20,000 yuan. The reimbursement ratio is different in different regions, and the price is also different, making it expensive. The price of the Turkish version of the original drug Trametinib listed overseas is around RMB 7,900 (the price may fluctuate due to the exchange rate). The price of the generic version of Trametinib produced by the Lao pharmaceutical factory is around RMB 2,950 (the price may fluctuate due to the exchange rate). The ingredients and efficacy of foreign generic drugs are basically the same as those of the domestic and foreign original drugs.