Is Trametinib available in China?

In December 2019, the National Medical Products Administration approved Trametinib (Trametinib) and dabrafenib, two original drugs for targeted combination therapy, to be launched in China for the treatment of BRAF For patients with V600 mutation-positive unresectable or metastatic melanoma and non-small cell lung cancer, due to the short time on the market, after entering the medical insurance ranks, the purchase may be limited to patients who meet the indications for trametinib. The reimbursement ratio is different in different regions. The price after reimbursement is different. Specifications The price of 2mg*30 tablets per box is around 10,000-20,000 yuan, which is expensive.

The main function of Trametinib is to inhibit the activity of MEK kinase in the cell signaling pathway thereby affecting the MAPK/ERK signaling pathway. This signaling pathway plays a key role in cancer cells. By inhibiting the activity of MEK kinase, Trametinib can reduce the growth and division of cancer cells and prevent the progression and spread of tumors. Trametinib can only be used under the supervision of a doctor. The dosage and usage will vary depending on the specific situation. The recommended dosage is 2mg, taken orally once a day. Some common side effects include skin reactions, tiredness, nausea, and more.

Specifications of the Turkish version of Trametinib original drug marketed overseasThe price of 2mg*30 tablets per box is around 7,900 RMB (the price may fluctuate due to exchange rates), and is also produced in other countries. The price of a box of 2mg*30 tablets produced by a Lao pharmaceutical factory for trametinib generics is around RMB 2,950 (the price may fluctuate due to exchange rates). The ingredients and efficacy of foreign generics are basically the same as those of domestic and foreign original drugs.