培美替尼价格多少？在哪买？

Pemetinib (also known as pemetinib, English trade name: pemazyre) is a selective fibroblast growth factor receptor (FGFR) inhibitor that inhibits FGFR1, FGFR2, and FGFR3. FGFRs play an important role in tumor cell proliferation, survival, migration, and neovascularization. The fusion, rearrangement, translocation and amplification of FGFRs genes are closely related to the occurrence and progression of various cancers. The FDA has granted Breakthrough Therapy designation for previously treated patients with advanced/metastatic or unresectable cholangiocarcinoma harboring an FGFR2 gene translocation, as well as Orphan Drug designation for the treatment of cholangiocarcinoma.

Indications for pemetinib include: (1) Cholangiocarcinoma that has metastasized (spread to other parts of the body) or is locally advanced and cannot be treated by surgery. (2) For the treatment of adults with diseases involving FGFR2 gene fusions or other changes in the FGFR2 gene structure. The FGFR-targeting drug pemetinib has been proven to have selective pharmacological activity against tumor cells with FGFR gene mutations in previous clinical studies. The effective ORR of this drug in the second-line treatment of patients with cholangiocarcinoma is 35.5%, and the disease control rate (DCR) is 82%.

How much does pemetinib cost? Where to buy? Because pemetinib is a new anti-tumor drug, it has not yet been launched in China, and patients cannot buy it in China. According to Medical Travel, there are three specifications of original drugs on sale in the United States, namely: 4.5 mg*14 tablets/box, 9 mg*14 tablets/box and 13.5 mg*14 tablets/box. The price of 13.5 mg*14 tablets/box is approximately US$17,800. If the patient needs medication or has other questions to consult, please contact the Medical Companion Travel Service.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.