2025年替莫唑胺正版的价格是多少？

Introduction: Temozolomide is an important chemotherapy drug used to treat malignant glioma and melanoma. Its price and medication regimen directly affect patients' treatment choices. This article will introduce in detail the market price of temozolomide in 2025, medication preparation matters, and medication precautions for special groups.

What is the genuine price of temozolomide in 2025?

Understanding the latest price information of temozolomide is crucial for patients to formulate treatment plans. There are significant differences in the prices of different versions of temozolomide in 2025. The prices are for reference only and the actual price shall prevail.

Domestic temozolomide price

Domestic temozolomide has been included in medical insurance. The winning bid price of medical insurance is approximately US$111, US$90, and US$231. The price after reimbursement will be lower and needs to be calculated according to the reimbursement ratio of each region.

Price of generic drugs

The price of generic temozolomide produced by Cipla in India is relatively low. The price of a box of 100mg*5 pills is about US$21, and the price of a box of 250mg*5 pills is about US$39.

Original drug prices

The price of original drugs is higher. Some patients with special needs can choose original drugs, but their financial affordability must be considered.

When choosing temozolomide, patients should comprehensively consider economic conditions, drug quality and treatment effects, and make an appropriate choice under the guidance of a doctor.

Preparation for administration of temozolomide

The correct use of temozolomide requires adequate preparation for administration.

Pre-medication examination

Basic examinations such as blood routine and liver and kidney function must be completed before starting treatment. These indicators will serve as baseline data for subsequent treatment monitoring.

Dose Calculation

The dose of temozolomide needs to be accurately calculated based on the patient’s body surface area. The standard dose is 75mg/m²/day for a total of 42 days, while receiving radiotherapy (60Gy in 30 fractions). Medication may be withheld based on patient tolerance, but dose reduction is not necessary.

Prevention of adverse reactions

Prepare antiemetic drugs in advance to prevent nausea and vomiting caused by chemotherapy. If necessary, the use of granulocyte colony-stimulating factor can be considered to prevent bone marrow suppression.

Adequate preparation for medication can improve treatment compliance, reduce the incidence of adverse reactions, and ensure smooth progress of treatment.

Temozolomide medication for special populations

Different populations have different tolerances and responses to temozolomide, and individualized medication plans are required.

Pediatric patients

Temozolomide is only used for pediatric patients 3 years old or older with recurrent or progressive malignant glioma. The safety and effectiveness of this drug in children under 3 years old have not yet been established.

Patients with liver and kidney dysfunction

Patients with mild to moderate liver and kidney dysfunction do not need to adjust the dose. Patients with severe liver and kidney dysfunction need to be extra cautious when using it and closely monitor relevant indicators.

Elderly patients

Elderly patients are at higher risk of developing neutropenia and thrombocytopenia. It is recommended to start with a lower dose and gradually adjust to the optimal therapeutic dose.

Temozolomide is a strictly regulated prescription drug. All patients should use it under the guidance of a professional physician and do not adjust the medication regimen on your own.