阿那莫林的作用功效和副作用是怎样的?

恶病质（cachexia）亦称恶液质，多由癌症和其他严重慢性病引起，阿那莫林也叫阿纳莫林，Anamorelin，Adlumiz，可用于癌症引起的恶病质患者。 Developed by Japan's Ono Pharmaceutical, it provides a new treatment option for patients with cancer cachexia who previously had no targeted drugs. So, what are the effects and side effects of Anamorelin?

What are the effects of Anamorelin?

阿那莫林是新型、口服、选择性的胃饥饿素受体激动剂，通过模拟胃肠道分泌出的胃饥饿素，从而有效改善癌症恶病质患者体重下降和丧失食欲的现象。胃饥饿素是一种主要由胃分泌的内源性肽，与其受体结合后，刺激多种途径对肌肉质量、体重、食欲、代谢进行正调节。

癌症恶液质在肿瘤的各个时期都有可能出现，发生率高达50%~60%，阿那莫林能改善患者的生活质量及疾病进展状况，对患者的病情能产生积极作用，具有抗炎、抑制肌肉蛋白质分解、增加脂肪堆积的作用。

Anamorelin side effects

阿那莫林的治疗效果虽然很好，但也是有副作用的，虚弱、疲劳、心房颤动、呼吸困难、肺炎 、贫血、血小板减少症、腹痛、焦虑等是，患者的病情和体质不同，用药后副作用的表现也是不一样的。

癌症恶液质的主观症状包括食欲下降、早饱、恶心、呕吐、味/嗅觉异常、乏力、疾病相关负荷、整体感觉较差；小细胞肺癌、胃癌、胰腺癌、结直肠癌等恶性肿瘤患者的恶液质病症都可以用阿那莫林治疗，效果显著。 The above is the content of the effects and side effects of Anamorelin.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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