2021抗癌新药阿那莫林上市，了解下这款抗癌新药背负的“使命”

Cancer is the common enemy of mankind today. Everyone is equal before cancer. Late-stage patients with cancer will be treated with drugs. Nowadays, many drugs have been developed for cancer and have good effects. It is an anti-cancer drug developed in Japan and is a newly launched drug in 2021. Anamorelin has now been approved in Japan and is used as the main drug for clinical cancer treatment.

Anamorelin indications

On April 21, 2021, the launch of Kojima Pharmaceutical's new anti-cancer drug Anamorelin heralds the addition of a general in the clinical treatment of cancer. Anamorelin is a ghrelin receptor agonist, mainly used to treat malignant tumors such as non-small cell lung cancer patients, gastric cancer patients, pancreatic cancer patients, and colorectal cancer patients.

The significance of anamorelin to the field of tumor treatment

Since its launch, anamorelin has been evaluated by authoritative organizations as a very important innovation in the field of oncology. Due to the difficulty of overall treatment of cancer cachexia, considerable treatment cannot be carried out to a large extent. However, with the launch of anamorelin, it marks that there is an additional "general" in the clinical treatment of cancer cachexia. It is a very important milestone in the clinical treatment of cancer cachexia.

Anamorelin pharmacological effects

Anamorelin is a novel, oral, selective ghrelin receptor agonist. Ghrelin is an endogenous peptide mainly secreted by the stomach. After binding to its receptor, it stimulates multiple pathways to positively regulate body weight, muscle mass, appetite and metabolism. By simulating ghrelin secreted from the gastrointestinal tract, anamulin can improve weight loss and loss of appetite in patients with cancer cachexia.

Anamorelin side effects and related treatments

1. Diarrhea and abdominal pain: When patients experience the side effects of abdominal pain and diarrhea, they should pay more attention to keeping the abdomen warm. If the diarrhea symptoms are tolerable, they can take antidiarrheal drugs. If the symptoms are severe and do not improve, it is recommended to consult a doctor for treatment.

2. Nausea and vomiting: Patients should start with diet, eat more light and easy-to-digest foods, eat small meals frequently, and eat less sweets and spicy foods.

3. Constipation: Take medicine, fresh fruits and vegetables, and drink plenty of water.

4. Stomatitis: Keep your mouth clean for a long time, rinse your mouth after meals and brush your teeth frequently.

5. Hand-foot syndrome: Skin care must be in place and the skin must be kept clean at all times. If necessary, antibiotics can be used locally on the skin.

6. Hypertension: Patients should monitor their blood pressure index at all times during medication and go to the hospital promptly if any abnormalities are found.

How effective is Anamorelin?

Anamorelin was approved in Japan in January 2021. The approval was mainly based on the results of 2 clinical studies conducted in Japan on patients with cancer cachexia:

1. A placebo-controlled, randomized, double-blind, parallel-group study in patients with non-small cell lung cancer (NSCLC).

2. An open-label, uncontrolled phase III study in patients with colorectal cancer, gastric cancer, and pancreatic cancer.

Clinical data show that anamorelin has the effect of increasing body weight, muscle mass, and appetite in patients with cancer cachexia. The launch of Anamorelin will provide a new treatment option for Japanese cancer cachexia patients who have no treatment options and help improve the quality of life of such patients.

Because Anamorelin has just been launched in China, many patients want to buy Anamorelin but cannot. Medical Companion Travel can provide patients with formal and reliable purchase channels for Anamorelin. Interested patients can consult the Medical Companion Travel Service to learn about the formal purchase channels for Anamorelin and specific quotation issues.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and to help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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