降压药依普利酮多少钱一盒
How much does a box of antihypertensive drugs cost? Eplerenone is an oral drug approved for marketing in the United States in 2002. It is a new highly selective aldosterone receptor blocker that can be used for the treatment of heart failure, hypertension, and coronary heart disease. Eplerenone blocks the binding of aldosterone, a component of the renin-angiotensin-aldosterone system (RAAS), by binding to the mineralocorticoid receptor. Currently, the most cost-effective product on the market is the Indian version of eplerenone, which is 50mg*100 tablets and costs around 420$.
Eplerenone is produced by Novartis in Switzerland and is the first selective aldosterone receptor antagonist. Studies have found that in vitro, the affinity of eplerenone for aldosterone receptors is 1/10 to 1/20 that of spironolactone, but its effectiveness in vivo is 50% to 75% of spironolactone. The 17α thioacetyl group of spironolactone is replaced by a methyl ester group, which significantly improves the selectivity of eplerenone for aldosterone receptors.
Eplerenone was approved for clinical use by the State Food and Drug Administration in 2002 and has definite efficacy in the treatment of hypertension, heart failure and myocardial infarction. Eplerenone is safe and well tolerated, making it a good alternative to spironolactone. Brings new options to the treatment of cardiovascular disease.
It has not yet been launched in my country, so it is not sold in domestic pharmacies or hospitals yet. If patients need to buy the Indian version of eplerenone, they can go abroad to buy it in person. They don’t have to worry about buying counterfeit drugs in regular pharmacies in India. If it is inconvenient to go abroad, you can contact a formal overseas medical consulting service company in China. Medical Companion Travel is a company specializing in transnational medical consulting. If you have purchasing needs, you can consult Medical Companion Travel Service.
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